I do not know whether this is possible or not but
We have a requirement to open an exe (My VB 2005 windows application on a local user's machine) through heyperlink in an email passing a parameter tothat exe)
I can create an HTML email with a link to my exe but not sure how can you pass a parameter to that exe?
<a href="file://C:/Myapppath/myexe.exe parameter1">Click to open this application</a>