I find that in the things I do, using the SelectionChangeCommitted works better (might be the case for you, but I thought I'd throw it out anyway) than using SelectedIndexChanged.
The difference between the two events is that SelectedIndexChanged fires anytime the SelectedItem is changed, whether it is programmatic (done by you) or by the user, which works most of the time, but can sometimes get funky when linking two (or more) combo boxes together. The SelectionChangeCommitted event only fires off when the user changes which item is selected.
michael harsh is definitely right though. Use an event of the Combo Box to detect when they selected a different item |