Thanks for your replay.
I am using XP. Clickonce works for Guest accout in a specific scenario. If you follow the following steps, clickonce will work for guest account:
1> 1> Logged in as an administrator.
2> 2> Run the clickonce application. Then you can close the application.
3> 3> Switch to Guest user account.
4> Install the clickonce application from Guest account. It will run!
Very weird scenario. However, it really works.
setu