I don't think it matters. IF the point is just to get a shortcut to show up for the user, I don'g see that this can hurt anything.
The only thing it's really doing is providing a link to the installation URL. ClickOnce applications are installed under the user's profile. So when each person logs in and clicks on your shortcut, they are basically installing the ClickOnce application under their profile.
You can install it under the administrator account until the cows come home, and it won't change the fact that each user has to have their own copy. Just FYI.
RobinDotNet
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